Article
Extending the discrete Laplace method: incorporating multi-copy loci, partial repeats and null alleles.
Forensic science international. Genetics - 1 Jul 2023
Kruijver Maarten, Taylor Duncan, Buckleton John
Abstract excerpt
The discrete Laplace method can be used to estimate the frequency of a Y-chromosomal STR haplotype using a random sample from the population. Two limitations of the method are the assumptions that each profile has exactly one allele at every locus and that this allele has an integer repeat number. We relax these assumptions to allow for multi-copy loci, partial repeats and null alleles. We show how the parameters...
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