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Novel Gene Clusters for Natural Product Synthesis Are Abundant in the Mangrove Swamp Microbiome

16 May 2023

Abstract excerpt

At present, the majority of known clinical drugs originated from cultivated species of a few bacterial lineages. It is vital for the development of new pharmaceuticals to explore the biosynthetic potential of naturally uncultivable microorganisms using new techniques. Based on the large numbers of genomes reconstructed from mangrove wetlands, we identified abundant and diverse biosynthetic gene clusters in...

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PMID: 37191511
DOI: 10.1128/aem.00102-23

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