Article
Type-2-low severe asthma endotypes for new treatments: the new asthma frontier.
Current opinion in allergy and clinical immunology - 1 Jun 2023
Chung Kian Fan
Abstract excerpt
PURPOSE OF REVIEW: Type-2 (T2)-high asthma represents a well defined group of severe eosinophilic asthma for which there are now effective biologic therapies targetting the interleukins (ILs) 4, 5 and 13, and Immunoglobulin E. T2-low asthma detected in the clinic by a low blood eosinophil count remains ill-defined and is the focus of this review. RECENT FINDINGS: By analysing transcriptomic and proteomic...
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