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Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity

12 May 2023

Abstract excerpt

BACKGROUND: MET-driven acquired resistance is emerging with unanticipated frequency in patients relapsing upon molecular therapy treatments. However, the determination of MET amplification remains challenging using both standard and next-generation sequencing-based methodologies. Liquid biopsy is an effective, non-invasive approach to define cancer genomic profiles, track tumor evolution over time, monitor...

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PMID: 37170152
DOI: 10.1186/s13046-023-02690-5

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