Article
Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability.
Neurosurgical review - 11 May 2023
Uchino Haruto, Ito Masaki, Tokairin Kikutaro, Tatezawa Ryota, Sugiyama Taku, Kazumata Ken, Fujimura Miki
Abstract excerpt
A cortical hyperintensity on fluid-attenuated inversion recovery images (FLAIR cortical hyperintensity (FCH)) is an abnormal finding after revascularization surgery for moyamoya disease. This study aimed to investigate the pathophysiology of FCH through genetic analyses of RNF213 p.R4810K polymorphism and perioperative hemodynamic studies using single-photon emission computed tomography. We studied 96 hemispheres...
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