Article
Fim3-dependent autoagglutination of Bordetella pertussis.
Scientific reports - 10 May 2023
Otsuka Nao, Koide Kentaro, Goto Masataka, Kamachi Kazunari, Kenri Tsuyoshi
Abstract excerpt
Autoagglutination (Agg) of Bordetella pertussis is often observed in clinical laboratory. However, its causal factors and frequency in circulating strains are unknown. Repeated single colony isolation enabled us to detect an Agg- mutant in the supernatant of an Agg+ strain of B. pertussis. Whole-genome sequencing and immunoblot analysis disclosed that the Agg- mutant had a single C-deletion in its fim3 promoter...
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