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Article

Perturbations in the airway microbiome are associated with type 2 asthma phenotype and severity.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Mar 2025

Zhang Wei, Li Lifei, Zhang Yu, Dai Junjie, Qiu Chen, Chen Rongchang, Shi Fei

Abstract excerpt

BACKGROUND: Airway microbiome has been linked to asthma heterogeneity, yet little is known about the associations between airway microbiota and type 2 (T2) asthma phenotype and severity. OBJECTIVE: To determine the relationship of nasopharyngeal (NP) and induced sputum (IS) microbiota to the phenotypic features of T2 asthma. METHODS: NP and IS samples from subjects with T2 mild-to-moderate asthma (n = 23),...

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Identifiers

PMID: 39549985
DOI: 10.1016/j.anai.2024.11.005

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