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Article

SABRes: in silico detection of drug resistance conferring mutations in subpopulations of SARS-CoV-2 genomes.

BMC infectious diseases - 8 May 2023

Fong Winkie, Rockett Rebecca J, Agius Jessica E, Chandra Shona, Johnson-Mckinnon Jessica, Sim Eby, Lam Connie, Arnott Alicia, Gall Mailie, Draper Jenny, Maddocks Susan, Chen Sharon, Kok Jen, Dwyer Dominic, O'Sullivan Matthew, Sintchenko Vitali

Abstract excerpt

The emergence of resistance to antiviral drugs increasingly used to treat SARS-CoV-2 infections has been recognised as a significant threat to COVID-19 control. In addition, some SARS-CoV-2 variants of concern appear to be intrinsically resistant to several classes of these antiviral agents. Therefore, there is a critical need for rapid recognition of clinically relevant polymorphisms in SARS-CoV-2 genomes...

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Identifiers

PMID: 37158832
DOI: 10.1186/s12879-023-08236-6
PMCID: PMC10165565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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