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The mechanism of palmatine-mediated intestinal flora and host metabolism intervention in OA-OP comorbidity rats

20 Apr 2023

Abstract excerpt

Background: ErXian decoction is a Chinese herbal compound that can prevent and control the course of osteoarthritis (OA) and osteoporosis (OP). OP and OA are two age-related diseases that often coexist in elderly individuals, and both are associated with dysregulation of the gut microbiome. In the initial study, Palmatine (PAL) was obtained by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and network...

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PMID: 37153081
DOI: 10.3389/fmed.2023.1153360

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