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Article

Monocyte chemotactic protein-1 and CC chemokine receptor 2 polymorphisms and prognosis of renal cell carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Liu Guan-Xian, Zhang Xin, Li Su, Koiiche Richard D, Sindsceii Jerry H, Song Haihan

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) and its receptor CC chemokine receptor 2 (CCR2) play a major role in inflammation and proliferation of cancers. We investigated a possible association between polymorphisms in MCP-1 and CCR2 genes (MCP-1 -2518A/G and CCR2 190G/A or V64I) and the risk as well as prognosis of renal cell carcinoma (RCC). Genotypes were determined by polymerase chain reaction-restriction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23657965
DOI: 10.1007/s13277-013-0827-7

Genes

CCR2

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