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Targeting DNA damage repair precision medicine strategies in cancer

4 May 2023

Abstract excerpt

DNA repair targeted therapeutics is a promising precision medicine strategy in cancer. The development and clinical use of PARP inhibitors has transformed lives for many patients with BRCA germline deficient breast and ovarian cancer as well as platinum sensitive epithelial ovarian cancers. However, lessons learnt from the clinical use of PARP inhibitors also confirm that not all patients respond either due to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37148685
DOI: 10.1016/j.coph.2023.102381

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