Article
Replication properties and immunomodulatory effects of human cytomegalovirus infection impact the clinical presentation in congenital patients: A case series.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2023
Spadavecchia Alessia, Cresi Francesco, Leone Agata, Dell'Oste Valentina, Biolatti Matteo, Galitska Ganna, Coscia Alessandra, Deantoni Sonia, Valenza Cinzia, Bertino Enrico, Peila Chiara
Abstract excerpt
BACKGROUND: Human cytomegalovirus (HCMV) is the leading cause of congenital infections resulting in severe morbidity and mortality among newborns worldwide. Although both the host's and the virus' genetic backgrounds contribute to the outcome of infections, significant gaps remain in our understanding of the exact mechanisms that determine disease severity. OBJECTIVES: In this study, we sought to identify a...
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