Article
Polymorphisms in inflammatory pathway genes, host factors and lung cancer risk in Chinese female never-smokers.
Carcinogenesis - 1 Apr 2011
Lim Wei-Yen, Chen Ying, Ali Safiyya Mohamed, Chuah Khoon Leong, Eng Philip, Leong Swan Swan, Lim Elaine, Lim Tow Keang, Ng Alan W K, Poh Wee Teng, Tee Augustine, Teh Ming, Salim Agus, Seow Adeline
Abstract excerpt
Inflammation appears to be important in lung carcinogenesis among smokers, but its role among never-smokers is not well established. We hypothesized that inflammatory medical conditions and gene polymorphisms interact to increase lung cancer risk in never-smokers. We interviewed 433 Singaporean female never-smoker lung cancer patients and 1375 hospital controls, and evaluated six polymorphisms in the interleukin...
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