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Article

A New Computational Deconvolution Algorithm for the Analysis of Forensic DNA Mixtures with SNP Markers.

Genes - 15 May 2022

Yin Yu, Zhang Peng, Xing Yu

Abstract excerpt

Single nucleotide polymorphisms (SNPs) support robust analysis on degraded DNA samples. However, the development of a systematic method to interpret the profiles derived from the mixtures is less studied, and it remains a challenge due to the bi-allelic nature of SNP markers. To improve the discriminating power of SNPs, this study explored bioinformatic strategies to analyze mixtures. Then, computer-generated...

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PMID: 35627269
DOI: 10.3390/genes13050884
PMCID: PMC9141285

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