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Article

Secondary post-geniculate involvement in Leber's hereditary optic neuropathy.

PloS one - 1 Jan 2012

Rizzo Giovanni, Tozer Kevin R, Tonon Caterina, Manners David, Testa Claudia, Malucelli Emil, Valentino Maria Lucia, La Morgia Chiara, Barboni Piero, Randhawa Ruvdeep S, Ross-Cisneros Fred N, Sadun Alfredo A, Carelli Valerio, Lodi Raffaele

Abstract excerpt

Leber's hereditary optic neuropathy (LHON) is characterized by retinal ganglion cell (RGC) degeneration with the preferential involvement of those forming the papillomacular bundle. The optic nerve is considered the main pathological target for LHON. Our aim was to investigate the possible involvement of the post-geniculate visual pathway in LHON patients. We used diffusion-weighted imaging for in vivo...

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Identifiers

PMID: 23209682
DOI: 10.1371/journal.pone.0050230
PMCID: PMC3507727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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