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Article

The TNF-α rs361525 and IFN-γ rs2430561 polymorphisms are associated with liver cirrhosis risk: a comprehensive meta-analysis.

Frontiers in immunology - 1 Jan 2023

Zheng Minghui, Li Jing, Fang Weizhen, Luo Ling, Ding Rui, Zeng Hua, Luo Hong, Lin Xianghua, Duan Chaohui

Abstract excerpt

Background: Inflammation serves as an essential driver of liver cirrhosis (LC) incidence. Accordingly, a meta-analysis was carried out to explore the association between specific polymorphisms in the interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) genes and the incidence of LC based on comparisons of genotype and allele frequencies. Objectives: To study the relationship between TNF-α rs361525 and IFN-γ...

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Identifiers

PMID: 37122734
DOI: 10.3389/fimmu.2023.1129767
PMCID: PMC10140545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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