Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma

Abstract excerpt

Angiosarcomas are rare malignant tumors of the endothelium, arising commonly from the head and neck region (AS-HN) and recently associated with ultraviolet (UV) exposure and human herpesvirus-7 infection. We examined 81 cases of angiosarcomas, including 47 cases of AS-HN, integrating information from whole genome sequencing, gene expression profiling and spatial transcriptomics (10X Visium). In the AS-HN cohort,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiac tumors and thrombi
• Share to Sarcoma Diagnosis and Treatment
• Share to Vascular Tumors and Angiosarcomas