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Initial development and testing of an exhaled microRNA detection strategy for lung cancer case–control discrimination

24 Apr 2023

Abstract excerpt

For detecting field carcinogenesis non-invasively, early technical development and case-control testing of exhaled breath condensate microRNAs was performed. In design, human lung tissue microRNA-seq discovery was reconciled with TCGA and published tumor-discriminant microRNAs, yielding a panel of 24 upregulated microRNAs. The airway origin of exhaled microRNAs was topographically "fingerprinted", using paired...

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PMID: 37095155
DOI: 10.1038/s41598-023-33698-8

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