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Analyses of single extracellular vesicles from non-small lung cancer cells to reveal effects of epidermal growth factor receptor inhibitor treatments.

Talanta - 1 Jul 2023

Stridfeldt Fredrik, Cavallaro Sara, Hååg Petra, Lewensohn Rolf, Linnros Jan, Viktorsson Kristina, Dev Apurba

Abstract excerpt

Precision cancer medicine has changed the treatment landscape of non-small cell lung cancer (NSCLC) as illustrated by the introduction of tyrosine kinase inhibitors (TKIs) towards mutated epidermal growth factor receptor (EGFR). However, as responses to EGFR-TKIs are heterogenous among NSCLC patients, there is a need for ways to early monitor changes in treatment response in a non-invasive way e.g., in patient's...

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PMID: 37084607
DOI: 10.1016/j.talanta.2023.124553

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