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Article

Unveiling mutational dynamics in non-small cell lung cancer patients by quantitative EGFR profiling in vesicular RNA.

Molecular oncology - 1 Sept 2021

Pasini Luigi, Notarangelo Michela, Vagheggini Alessandro, Burgio Marco Angelo, Crinò Lucio, Chiadini Elisa, Prochowski Andrea Iamurri, Delmonte Angelo, Ulivi Paola, D'Agostino Vito Giuseppe

Abstract excerpt

The mutational status of the epidermal growth factor receptor (EGFR) guides the stratification of non-small cell lung cancer (NSCLC) patients for treatment with tyrosine kinase inhibitors (TKIs). A liquid biopsy test on cell-free DNA is recommended as a clinical decision-supporting tool, although it has limited sensitivity. Here, we comparatively investigated the extracellular vesicle (EV)-RNA as an independent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33942501
DOI: 10.1002/1878-0261.12976
PMCID: PMC8410558

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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