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Species-specific MARCO-alphavirus interactions dictate chikungunya virus viremia

21 Apr 2023

Abstract excerpt

Arboviruses are public health threats that cause explosive outbreaks. Major determinants of arbovirus transmission, geographic spread, and pathogenesis are the magnitude and duration of viremia in vertebrate hosts. Previously, we determined that multiple alphaviruses are cleared efficiently from murine circulation by the scavenger receptor MARCO (Macrophage receptor with collagenous structure). Here, we define...

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PMID: 37083332
DOI: 10.1016/j.celrep.2023.112418

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