Article
Treatment Refractory Soft Tissue Myoepithelial Carcinoma With an ARID1A Mutation.
Journal of pediatric hematology/oncology - 1 May 2023
Ashcroft Cody R, Penney Scott W, Whiteway Susan L
Abstract excerpt
Soft tissue myoepithelial carcinoma is a rare tumor first reported in the salivary gland. There is considerable tumor heterogeneity between pathology findings, tumor aggressiveness, and response to treatment. Recent molecular testing has identified recurrent genetic changes with PLAG mutations in salivary gland primary tumors and loss of SMARCB1 and EWSR1/FUS gene changes in myoepithelial carcinoma. SMARCB1 is a...
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