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Dissecting the roles and clinical potential of YY1 in the tumor microenvironment

4 Apr 2023

Abstract excerpt

Yin-Yang 1 (YY1) is a member of the GLI-Kruppel family of zinc finger proteins and plays a vital dual biological role in cancer as an oncogene or a tumor suppressor during tumorigenesis and tumor progression. The tumor microenvironment (TME) is identified as the "soil" of tumor that has a critical role in both tumor growth and metastasis. Many studies have found that YY1 is closely related to the remodeling and...

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Identifiers

PMID: 37081988
DOI: 10.3389/fonc.2023.1122110

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