Article
Use of High-Resolution Geospatial and Genomic Data to Characterize Recent Tuberculosis Transmission, Botswana.
Emerging infectious diseases - 1 May 2023
Baker Chelsea R, Barilar Ivan, de Araujo Leonardo S, Rimoin Anne W, Parker Daniel M, Boyd Rosanna, Tobias James L, Moonan Patrick K, Click Eleanor S, Finlay Alyssa, Oeltmann John E, Minin Vladimir N, Modongo Chawangwa, Zetola Nicola M, Niemann Stefan, Shin Sanghyuk S
Abstract excerpt
Combining genomic and geospatial data can be useful for understanding Mycobacterium tuberculosis transmission in high-burden tuberculosis (TB) settings. We performed whole-genome sequencing on M. tuberculosis DNA extracted from sputum cultures from a population-based TB study conducted in Gaborone, Botswana, during 2012-2016. We determined spatial distribution of cases on the basis of shared genotypes among...
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