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satmut_utils: a simulation and variant calling package for multiplexed assays of variant effect.

Genome biology - 20 Apr 2023

Hoskins Ian, Sun Song, Cote Atina, Roth Frederick P, Cenik Can

Abstract excerpt

The impact of millions of individual genetic variants on molecular phenotypes in coding sequences remains unknown. Multiplexed assays of variant effect (MAVEs) are scalable methods to annotate relevant variants, but existing software lacks standardization, requires cumbersome configuration, and does not scale to large targets. We present satmut_utils as a flexible solution for simulation and variant...

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Identifiers

PMID: 37081510
DOI: 10.1186/s13059-023-02922-z
PMCID: PMC10116734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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