Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect.

Genome biology - 4 Nov 2019

Esposito Daniel, Weile Jochen, Shendure Jay, Starita Lea M, Papenfuss Anthony T, Roth Frederick P, Fowler Douglas M, Rubin Alan F

Abstract excerpt

Multiplex assays of variant effect (MAVEs), such as deep mutational scans and massively parallel reporter assays, test thousands of sequence variants in a single experiment. Despite the importance of MAVE data for basic and clinical research, there is no standard resource for their discovery and distribution. Here, we present MaveDB ( https://www.mavedb.org ), a public repository for large-scale measurements of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Genetic
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 31679514
DOI: 10.1186/s13059-019-1845-6
PMCID: PMC6827219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect.PMID 31679514Read ↗

An open-source platform to distribute and interpret data from multiplexed assays of variant effectSemantic proximity Read ↗

MaveRegistry: a collaboration platform for multiplexed assays of variant effectSemantic proximity Read ↗

MaveQuest: a web resource for planning experimental tests of human variant effects.Semantic proximity Read ↗

MaveMD: A functional data resource for genomic medicineSemantic proximity Read ↗

satmut_utils: a simulation and variant calling package for multiplexed assays of variant effect.Semantic proximity Read ↗

Multiplexed assays of variant effects contribute to a growing genotype-phenotype atlas.Semantic proximity Read ↗

Variant scoring tools for deep mutational scanning.Semantic proximity Read ↗

Mapping MAVE data for use in human genomics applicationsSemantic proximity Read ↗

DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies.Semantic proximity Read ↗

satmut_utils: a simulation and variant calling package for multiplexed assays of variant effectSemantic proximity Read ↗

MuCor: mutation aggregation and correlation.Semantic proximity Read ↗

Recommendations for the collection and use of multiplexed functional data for clinical variant interpretation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.