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Article

Cardiomyocyte maturation and its reversal during cardiac regeneration

11 Dec 2022

Abstract excerpt

Cardiovascular disease is a leading cause of death worldwide. Due to the limited proliferative and regenerative capacity of adult cardiomyocytes, the lost myocardium is not replenished efficiently and is replaced by a fibrotic scar, which eventually leads to heart failure. Current therapies to cure or delay the progression of heart failure are limited; hence, there is a pressing need for regenerative approaches...

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PMID: 36502296
DOI: 10.1002/dvdy.557

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