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Discovery of New Siderophores from a Marine Streptomycetes sp. via Combined Metabolomics and Analysis of Iron-Chelating Activity

19 Apr 2023

Abstract excerpt

The marine-derived Streptomyces sp. FIMYZ-003 strain was found to produce novel siderophores with yields negatively correlated with the iron concentration in the medium. Mass spectrometry (MS)-based metabolomics coupled with metallophore assays identified two novel α-hydroxycarboxylate-type siderophores, fradiamines C and D ( 3 and 4 ), together with two related known siderophores, fradiamines A and B ( 1 and 2...

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PMID: 37076425
DOI: 10.1021/acs.jafc.3c00234

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