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Familial aggregation of early-onset cancers in early-onset breast cancer families.

International journal of cancer - 15 Jul 2023

Rantala Jasmiina N J, Heikkinen Sanna M M, Hirvonen Elli M, Tanskanen Tomas, Malila Nea K, Pitkäniemi Janne M

Abstract excerpt

The risk of early-onset (EO) breast cancer is known to be increased in relatives of EO breast cancer patients, but less is known about the familial risk of other EO cancers. We assessed familial risks of EO cancers (aged ≤40 years) other than breast cancer in 54 753 relatives of 5562 women with EO breast cancer (probands) by using a population-based cohort from Finland. Standardized incidence ratios (SIRs) and...

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PMID: 37074269
DOI: 10.1002/ijc.34538

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