Article
Familial cancer risk in family members and spouses of patients with early-onset head and neck cancer.
Head & neck - 1 Sept 2020
Mroueh Rayan, Tanskanen Tomas, Haapaniemi Aaro, Salo Tuula, Malila Nea, Mäkitie Antti, Pitkäniemi Janne
Abstract excerpt
BACKGROUND: Reported patterns of familial aggregation of head and neck cancer (HNC) vary greatly, with many studies hampered by the limited number of subjects. METHODS: Altogether 923 early-onset (≤40 years old) HNC probands, their first-degree relatives, spouses, and siblings' offspring were ascertained. Cumulative risk and standardized incidence ratios (SIRs) were estimated. RESULTS: Of all early-onset HNC...
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