Article
Synchronous thyroid cancer and malignant struma ovarii: concordant mutations and microRNA profile, discordant loss of heterozygosity loci.
Diagnostic pathology - 18 Apr 2023
Seo Gabriella T, Minkowitz Jeremy, Kapustin Danielle A, Fan Jun, Minkowitz Gerald, Minkowitz Miriam, Dowling Eric, Matloob Ammar, Asti Divya, Dhar Meekoo, Shutty Christopher, Brickman Alan, Urken Mark L, Brandwein-Weber Margaret, Finkelstein Sydney D
Abstract excerpt
BACKGROUND: Struma ovarii is an unusual ovarian teratoma containing predominantly thyroid tissue. Less than 10% of cases undergo malignant transformation in the thyroid tissue and are considered malignant struma ovarii (MSO). MSO have been reported with concurrent thyroid lesions, but molecular data is lacking. CASE PRESENTATION: A 42-year-old female developed MSO and synchronous multifocal subcentimeter...
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