Article
RAS mutation-positive follicular variant of papillary thyroid carcinoma arising in a struma ovarii.
Endocrine pathology - 1 Jun 2010
Coyne Christopher, Nikiforov Yuri E
Abstract excerpt
Struma ovarii is an ovarian mature teratoma composed exclusively or predominantly of thyroid tissue. Malignant transformation of struma ovarii is rare and poorly understood, although this process is thought to be similar to carcinogenesis in malignant tumors of differentiated thyroid tissue originating in the thyroid gland. Genetic alterations in the mitogen-activated protein kinase pathway, including mutations...
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