Article
GBC: a parallel toolkit based on highly addressable byte-encoding blocks for extremely large-scale genotypes of species.
Genome biology - 17 Apr 2023
Zhang Liubin, Yuan Yangyang, Peng Wenjie, Tang Bin, Li Mulin Jun, Gui Hongsheng, Wang Qiang, Li Miaoxin
Abstract excerpt
Whole -genome sequencing projects of millions of subjects contain enormous genotypes, entailing a huge memory burden and time for computation. Here, we present GBC, a toolkit for rapidly compressing large-scale genotypes into highly addressable byte-encoding blocks under an optimized parallel framework. We demonstrate that GBC is up to 1000 times faster than state-of-the-art methods to access and manage...
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