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Article

Expression Quantitative Trait Methylation Analysis Identifies Whole Blood Molecular Footprint in Fetal Alcohol Spectrum Disorder (FASD).

International journal of molecular sciences - 1 Apr 2023

Krzyzewska Izabela M, Lauffer Peter, Mul Adri N, van der Laan Liselot, Yim Andrew Y F Li, Cobben Jan Maarten, Niklinski Jacek, Chomczyk Monika A, Smigiel Robert, Mannens Marcel M A M, Henneman Peter

Abstract excerpt

Fetal alcohol spectrum disorder (FASD) encompasses neurodevelopmental disabilities and physical birth defects associated with prenatal alcohol exposure. Previously, we attempted to identify epigenetic biomarkers for FASD by investigating the genome-wide DNA methylation (DNAm) profiles of individuals with FASD compared to healthy controls. In this study, we generated additional gene expression profiles in a subset...

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PMID: 37047575
DOI: 10.3390/ijms24076601
PMCID: PMC10095438

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