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Article

Fetal alcohol spectrum disorders: Genetic and epigenetic mechanisms

9 May 2020

Abstract excerpt

Fetal alcohol spectrum disorders (FASD) are a consequence of prenatal alcohol exposure (PAE). The etiology of the complex FASD phenotype with growth deficit, birth defects, and neurodevelopmental impairments is under extensive research. Both genetic and environmental factors contribute to the wide phenotype: chromosomal rearrangements, risk and protective alleles, environmental-induced epigenetic alterations as...

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PMID: 32386259
DOI: 10.1002/pd.5731

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