Serum-based BRAF V600E detection improves early diagnosis of papillary thyroid carcinoma: A prospective diagnostic accuracy study compared with ultrasound-guided cytology.

Abstract excerpt

Accurate preoperative diagnosis of papillary thyroid carcinoma (PTC) remains difficult, especially for small thyroid nodules and lesions with indeterminate cytology. This prospective diagnostic study evaluated the clinical value of serum-based v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) V600E mutation detection and its performance in combination with ultrasound-guided fine-needle aspiration cytology...

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• Biopsy, Fine-Needle
• Carcinoma
• Carcinoma, Papillary
• Early Detection of Cancer
• Thyroid Cancer, Papillary