Article
Screening of single nucleotide polymorphisms within HLA region related to hematopoietic stem cell transplantation using MassARRAY technology.
Scientific reports - 11 Apr 2023
Tsai Shu-Hui, Chang Pi-Yueh, Wen Ying-Hao, Lin Wei-Tzu, Hsu Fang-Ping, Chen Ding-Ping
Abstract excerpt
A growing number of studies showed that single nucleotide polymorphisms (SNPs) in the human leukocyte antigen (HLA)-related genes were associated with the outcome of hematopoietic stem cell transplantation (HSCT). Thus, other SNPs located nearby the classical HLA genes must be considered in HSCT. We evaluated the clinical feasibility of MassARRAY by comparing to Sanger sequencing. The PCR amplicons with each one...
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