Article
Heritability Estimation of Cognitive Phenotypes in the ABCD Study® Using Mixed Models.
Behavior genetics - 1 May 2023
Smith Diana M, Loughnan Robert, Friedman Naomi P, Parekh Pravesh, Frei Oleksandr, Thompson Wesley K, Andreassen Ole A, Neale Michael, Jernigan Terry L, Dale Anders M
Abstract excerpt
Twin and family studies have historically aimed to partition phenotypic variance into components corresponding to additive genetic effects (A), common environment (C), and unique environment (E). Here we present the ACE Model and several extensions in the Adolescent Brain Cognitive Development℠ Study (ABCD Study®), employed using the new Fast Efficient Mixed Effects Analysis (FEMA) package. In the twin sub-sample...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.