Association of Intelectin 1 Gene rs2274907 A > T Polymorphism with Obesity, Type 2 Diabetes, Serum Intelectin-1 Levels and Lipid Profiles in Turkish Adults.

doi:10.1007/s10528-023-10371-3

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Association of Intelectin 1 Gene rs2274907 A > T Polymorphism with Obesity, Type 2 Diabetes, Serum Intelectin-1 Levels and Lipid Profiles in Turkish Adults.

Biochemical genetics - 1 Dec 2023

Guclu-Geyik Filiz, Koseoglu Pınar, Guven Gamze, Can Gunay, Kaya Aysem, Coban Neslihan, Komurcu-Bayrak Evrim, Erginel-Unaltuna Nihan

Abstract excerpt

The anti-inflammatory adipokine intelectin-1, which is encoded by the ITLN1 gene, is hypothesized to be linked to the pathogenesis of type 2 diabetes (T2DM) and obesity. The purpose of this study was to examine the effect of the ITLN1 gene polymorphism rs2274907 on obesity and T2DM in Turkish adults. The impact of genotype on lipid profiles and serum intelectin levels in the obese and diabetes groups was also...

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PMID: 37020118
DOI: 10.1007/s10528-023-10371-3

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