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In vivo adaptive antimicrobial resistance in Klebsiella pneumoniae during antibiotic therapy

16 Mar 2023

Abstract excerpt

Klebsiella pneumoniae is one of the leading pathogens contributing to antimicrobial resistance. The emergence of carbapenem-resistant K. pneumoniae (CRKP) has put the use of clinical antimicrobial agents in a dilemma. In particular, CRKP exhibiting resistance to ceftazidime/avibactam, tigecycline and colistin have raised great clinical concern, as these are the last-resort antibiotics for the treatment of CRKP...

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PMID: 37007508
DOI: 10.3389/fmicb.2023.1159912

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