Article
The Role of Gender Pharmacogenetics in the Personalization of Drug Treatment.
The Journal of pharmacology and experimental therapeutics - 1 Aug 2023
Cecchin Erika, Posocco Bianca, Mezzalira Silvia, Appetecchia Marialuisa, Toffoli Giuseppe
Abstract excerpt
The use of pharmacogenetic guidelines in personalizing treatments has shown the potential to reduce interindividual variability in drug response by enabling genotype-matched dosing and drug selection. However, other important factors, such as patient gender, may interact strongly with pharmacogenetics in determining the individual profile of toxicity and efficacy but are still rarely considered when planning...
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