Article
Gender based differences, pharmacogenetics and adverse events in chronic pain management.
The pharmacogenomics journal - 1 Apr 2020
Planelles Beatriz, Margarit César, Inda María-Del-Mar, Ballester Pura, Muriel Javier, Barrachina Jordi, Ajo Raquel, Esteban María-Dolores, Peiró Ana M
Abstract excerpt
Safety data in chronic non-cancer pain (CNCP) with long-term opioid therapy has been poorly studied and can be differently influenced by gender. Furthermore, pharmacogenetics (PGx) could possibly be used to tailor pain medication based on the individual's genetic background. The aim was to assess whether PGx applied to a pharmacovigilance system could help to improve a patient's security profile. A...
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