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Article

Blue cone monochromacy and gene therapy.

Vision research - 1 Jul 2023

Sechrest Emily R, Chmelik Kathryn, Tan Wendy D, Deng Wen-Tao

Abstract excerpt

Blue cone monochromacy (BCM) is a congenital vision disorder characterized by complete loss or severely reduced long- and middle-wavelength cone function, caused by mutations in the OPN1LW/OPN1MW gene cluster on the X-chromosome. BCM patients typically suffer from poor visual acuity, severely impaired color discrimination, myopia, and nystagmus. In this review, we cover the genetic causes of BCM, clinical...

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Identifiers

PMID: 37001420
DOI: 10.1016/j.visres.2023.108221
PMCID: PMC10182257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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