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Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation

30 Mar 2023

Abstract excerpt

Advanced glycation end products (AGEs) in lens proteins increase with aging, thus inducing cataracts and/or presbyopia. Hesperetin (Hst), which is an abundant plant flavanone largely derived from citrus species, and its derivatives attenuate cataracts and presbyopia in vivo and in vitro; however, no reports have described its effects on AGE formation in lens proteins. The present study demonstrated that AGEs in...

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PMID: 36999595
DOI: 10.3892/mmr.2023.12990

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