Article
Adeno-associated virus 2 infection in children with non-A-E hepatitis.
Nature - 1 May 2023
Ho Antonia, Orton Richard, Tayler Rachel, Asamaphan Patawee, Herder Vanessa, Davis Chris, Tong Lily, Smollett Katherine, Manali Maria, Allan Jay, Rawlik Konrad, McDonald Sarah E, Vink Elen, Pollock Louisa, Gannon Louise, Evans Clair, McMenamin Jim, Roy Kirsty, Marsh Kimberly, Divala Titus, Holden Matthew T G, Lockhart Michael, Yirrell David, Currie Sandra, O'Leary Maureen, Henderson David, Shepherd Samantha J, Jackson Celia, Gunson Rory, MacLean Alasdair, McInnes Neil, Bradley-Stewart Amanda, Battle Richard, Hollenbach Jill A, Henderson Paul, Odam Miranda, Chikowore Primrose, Oosthuyzen Wilna, Chand Meera, Hamilton Melissa Shea, Estrada-Rivadeneyra Diego, Levin Michael, Avramidis Nikos, Pairo-Castineira Erola, Vitart Veronique, Wilkie Craig, Palmarini Massimo, Ray Surajit, Robertson David L, da Silva Filipe Ana, Willett Brian J, Breuer Judith, Semple Malcolm G, Turner David, Baillie J Kenneth, Thomson Emma C
Abstract excerpt
An outbreak of acute hepatitis of unknown aetiology in children was reported in Scotland1 in April 2022 and has now been identified in 35 countries2. Several recent studies have suggested an association with human adenovirus with this outbreak, a virus not commonly associated with hepatitis. Here we report a detailed case-control investigation and find an association between adeno-associated virus 2 (AAV2)...
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