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Multiplex MinION sequencing suggests enteric adenovirus F41 genetic diversity comparable to pre-COVID-19 era.

Microbial genomics - 1 Jan 2023

Maes Mailis, Khokhar Fahad, Wilkinson Sam A J, Smith Andrew D, Kovalenko Ganna, Dougan Gordon, Quick Joshua, Loman Nicholas J, Baker Stephen, Curran Martin D, Skittrall Jordan P, Houldcroft Charlotte J

Abstract excerpt

Human adenovirus F41 causes acute gastroenteritis in children, and has recently been associated with an apparent increase in paediatric hepatitis of unknown aetiology in the UK, with further cases reported in multiple countries. Relatively little is known about the genetic diversity of adenovirus F41 in UK children; and it is unclear what, if any, impact the COVID-19 pandemic has had on viral diversity in the UK....

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PMID: 36748435
DOI: 10.1099/mgen.0.000920
PMCID: PMC9973849

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