Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of Baculoviruses as Gene Therapy Vectors for Brain Cancer

22 Feb 2023

Abstract excerpt

We aimed to assess the potential of baculoviral vectors (BV) for brain cancer gene therapy. We compared them with adenoviral vectors (AdV), which are used in neuro-oncology, but for which there is pre-existing immunity. We constructed BVs and AdVs encoding fluorescent reporter proteins and evaluated their transduction efficiency in glioma cells and astrocytes. Naïve and glioma-bearing mice were intracranially...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36992317
DOI: 10.3390/v15030608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of Baculoviruses as Gene Therapy Vectors for Brain CancerPMID 36992317Read ↗

Targeting microglia with lentivirus and AAV: Recent advances and remaining challengesSemantic proximity Read ↗

Virus-Based Therapies for the Treatment of Recurrent High-Grade GliomaSemantic proximity Read ↗

Lentiviral Vectors as Tools for the Study and Treatment of GlioblastomaSemantic proximity Read ↗

Strategies in Gene Therapy for GlioblastomaSemantic proximity Read ↗

Routes of administration for adeno-associated viruses carrying gene therapies for brain diseasesSemantic proximity Read ↗

Therapeutic efficacy of an immune stimulatory gene therapy strategy in a mouse model of high grade brainstem gliomaSemantic proximity Read ↗

Comparative analysis of microglia-targeted AAVs reveals capsid choice drives efficiency <i>in vitro</i> but has limited impact <i>in vivo</i>Semantic proximity Read ↗

Viral vectors in neurodegenerative diseases: immune responses and therapeutic applicationsSemantic proximity Read ↗

Development of an AAV Vector System for Highly Specific and Efficient Gene Expression in MicrogliaSemantic proximity Read ↗

Viral Microglia Reprogramming Clears Oligomeric Neurotoxic DebrisSemantic proximity Read ↗

Simple and Highly Specific Targeting of Resident Microglia with Adeno-Associated VirusSemantic proximity Read ↗

Advances and potential pitfalls of oncolytic viruses expressing immunomodulatory transgene therapy for malignant gliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.