Article
Consortium-based genome-wide meta-analysis for childhood dental caries traits.
Human molecular genetics - 1 Sept 2018
Haworth Simon, Shungin Dmitry, van der Tas Justin T, Vucic Strahinja, Medina-Gomez Carolina, Yakimov Victor, Feenstra Bjarke, Shaffer John R, Lee Myoung Keun, Standl Marie, Thiering Elisabeth, Wang Carol, Bønnelykke Klaus, Waage Johannes, Jessen Leon Eyrich, Nørrisgaard Pia Elisabeth, Joro Raimo, Seppälä Ilkka, Raitakari Olli, Dudding Tom, Grgic Olja, Ongkosuwito Edwin, Vierola Anu, Eloranta Aino-Maija, West Nicola X, Thomas Steven J, McNeil Daniel W, Levy Steven M, Slayton Rebecca, Nohr Ellen A, Lehtimäki Terho, Lakka Timo, Bisgaard Hans, Pennell Craig, Kühnisch Jan, Marazita Mary L, Melbye Mads, Geller Frank, Rivadeneira Fernando, Wolvius Eppo B, Franks Paul W, Johansson Ingegerd, Timpson Nicholas J
Abstract excerpt
Prior studies suggest dental caries traits in children and adolescents are partially heritable, but there has been no large-scale consortium genome-wide association study (GWAS) to date. We therefore performed GWAS for caries in participants aged 2.5-18.0 years from nine contributing centres. Phenotype definitions were created for the presence or absence of treated or untreated caries, stratified by primary and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.