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Article

Gram-negative bacteria resist antimicrobial agents by a DzrR-mediated envelope stress response

29 Mar 2023

Abstract excerpt

BACKGROUND: Envelope stress responses (ESRs) are critical for adaptive resistance of Gram-negative bacteria to envelope-targeting antimicrobial agents. However, ESRs are poorly defined in a large number of well-known plant and human pathogens. Dickeya oryzae can withstand a high level of self-produced envelope-targeting antimicrobial agents zeamines through a zeamine-stimulated RND efflux pump DesABC. Here, we...

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PMID: 36978084
DOI: 10.1186/s12915-023-01565-7

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