Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of l,d-Transpeptidase A Induces Dispensability of Rod Complex in Escherichia coli.

ACS infectious diseases - 8 Nov 2024

Gupta Rinki, Bhando Timsy, Pathania Ranjana

Abstract excerpt

Antimicrobial resistance (AMR) is a significant global threat, and the presence of resistance-determinant genes is one of the major driving forces behind it. The bacterial rod complex is an essential set of proteins that is crucial for cell survival due to its role in cell wall biogenesis and shape maintenance. Therefore, these proteins offer excellent potential as drug targets; however, compensatory mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Bacterial Proteins
Share to Cytoskeletal Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Escherichia coli

Share to Escherichia coli Proteins

Share to Gene Expression Regulation, Bacterial

Share to Microbial Sensitivity Tests

Source

Identifiers

PMID: 39412350
DOI: 10.1021/acsinfecdis.4c00597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of l,d-Transpeptidase A Induces Dispensability of Rod Complex in Escherichia coli.PMID 39412350Read ↗

Same same but different – The global response of <i>Escherichia coli</i> to five different LpxC inhibitorsSemantic proximity Read ↗

The phenotypic landscape of the mycobacterial cellSemantic proximity Read ↗

Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin ResistanceSemantic proximity Read ↗

Molecular Characterization of the Burkholderia cenocepacia dcw Operon and FtsZ Interactors as New Targets for Novel Antimicrobial DesignSemantic proximity Read ↗

Resistance in gram-negative bacilli: the emergence of RND efflux pumpsSemantic proximity Read ↗

One ring to rule them all: Current trends in combating bacterial resistance to the β‐lactamsSemantic proximity Read ↗

A ban on BAM: an update on inhibitors of the β-barrel assembly machinery.Semantic proximity Read ↗

RecA: a universal drug target in pathogenic bacteria.Semantic proximity Read ↗

TetR and OmpR family regulators in natural product biosynthesis and resistanceSemantic proximity Read ↗

<i>Escherichia coli</i> B-strains are intrinsically resistant to colistin and not suitable for characterization and identification of <i>mcr</i> genesSemantic proximity Read ↗

Mutational Activation of Antibiotic-Resistant Mechanisms in the Absence of Major Drug Efflux Systems of Escherichia coli.Semantic proximity Read ↗

New insights into the regulatory pathways associated with the activation of the stringent response in bacterial resistance to the PBP2-targeted antibiotics, mecillinam and OP0595/RG6080.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.